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M Arai Selected Research

N-methyldeoxynojirimycin

7/2001Combination of N-methyl-1-deoxynojirimycin and ischemic preconditioning markedly reduces the size of myocardial infarcts in rabbits.
7/2001Role of protein kinase C in the reduction of infarct size by N-methyl-1-deoxynojirimycin, an alpha-1,6-glucosidase inhibitor.
1/2000N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly improves postischemic left ventricular dysfunction.

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M Arai Research Topics

Disease

7Myocardial Infarction
10/2001 - 03/2000
6Fibrosis (Cirrhosis)
02/2016 - 03/2000
6Infarction (Infarctions)
10/2001 - 03/2000
5Ischemia
10/2001 - 01/2000
4Neoplasms (Cancer)
06/2018 - 06/2001
4Hemophilia A (Haemophilia)
05/2004 - 06/2001
4Liver Cirrhosis (Hepatic Cirrhosis)
10/2001 - 03/2000
4Heart Failure
06/2001 - 01/2000
4Reperfusion Injury
04/2001 - 03/2000
3Infections
02/2016 - 03/2000
3Carcinoma (Carcinomatosis)
01/2010 - 03/2005
3Coronary Occlusion
10/2001 - 03/2000
2Retinal Perforations
05/2017 - 12/2009
2Retinal Detachment (Retinal Detachments)
05/2017 - 12/2009
2Chronic Hepatitis B
02/2015 - 10/2011
2Hemorrhage
09/2009 - 06/2001
2Sepsis (Septicemia)
03/2008 - 01/2001
2Poliomyelitis (Polio)
06/2007 - 08/2006
2Body Weight (Weight, Body)
05/2004 - 01/2001
2Parkinsonian Disorders (Parkinsonism)
01/2003 - 10/2000
2Neuroblastoma
07/2001 - 05/2001
2Myocarditis (Carditis)
01/2001 - 01/2000
1Opioid-Induced Constipation
06/2018
1Treatment-Resistant Schizophrenia
11/2017
1Cataract (Cataracts)
05/2017
1Proliferative Vitreoretinopathy
05/2017
1Adenoma (Adenomas)
01/2016
1Alveolar Bone Loss
08/2014
1Osteoporosis
08/2014
1Crohn Disease (Crohn's Disease)
11/2012
1Ulcerative Colitis
10/2012
1Liver Diseases (Liver Disease)
02/2012
1Hepatocellular Carcinoma (Hepatoma)
10/2011
1Diabetes Mellitus
09/2011
1Osteoarthritis
07/2009

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
11/2017 - 04/2000
5Messenger RNA (mRNA)IBA
07/2009 - 01/2000
3Factor VIII (Coagulation Factor VIII)IBA
05/2004 - 10/2001
3Glycogen Debranching Enzyme System (Glycogen Debranching Enzyme)IBA
08/2001 - 01/2000
3N-methyldeoxynojirimycinIBA
07/2001 - 01/2000
3Protein Kinase CIBA
07/2001 - 01/2001
2AntibodiesIBA
11/2017 - 05/2004
2Retinaldehyde (Retinal)IBA
05/2017 - 07/2006
2SeprafilmIBA
05/2017 - 12/2009
2RNA (Ribonucleic Acid)IBA
02/2016 - 03/2000
2Adrenal Cortex Hormones (Corticosteroids)IBA
02/2015 - 08/2000
2Pharmaceutical PreparationsIBA
10/2012 - 08/2001
2Indicators and Reagents (Reagents)IBA
01/2010 - 01/2000
2CarbonIBA
06/2007 - 08/2006
2Biological ProductsIBA
01/2006 - 03/2000
2recombinant FVIIa (rFVIIa)FDA Link
03/2004 - 06/2001
2Hemostatics (Antihemorrhagics)IBA
10/2001 - 06/2001
2Matrix Metalloproteinases (MMPs)IBA
10/2001 - 03/2000
2Anti-Bacterial Agents (Antibiotics)IBA
09/2001 - 01/2001
2Glycoside Hydrolase InhibitorsIBA
08/2001 - 01/2000
2LipidsIBA
08/2001 - 04/2001
2Nicorandil (SG 75)IBA
08/2001 - 02/2000
2Adenosine Triphosphate (ATP)IBA
08/2001 - 03/2001
2Lactic Acid (Lactate)FDA LinkGeneric
07/2001 - 01/2000
2Collagenases (Collagenase)FDA Link
06/2001 - 08/2000
2Hydroxyl RadicalIBA
03/2001 - 03/2000
2Free Radical ScavengersIBA
03/2001 - 03/2000
2KATP ChannelsIBA
01/2001 - 02/2000
2Interleukin-18 (Interleukin 18)IBA
12/2000 - 07/2000
2Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
08/2000 - 03/2000
1Narcotic Antagonists (Opioid Antagonists)IBA
06/2018
1naldemedineIBA
06/2018
1Immunoglobulin G (IgG)IBA
02/2016
1Immunoglobulin A (IgA)IBA
02/2016
1SolutionsIBA
01/2016
1MutL Protein Homolog 1IBA
01/2016
1NucleosidesIBA
02/2015
1Butoxamine (Butaxamine)IBA
08/2014
1Infliximab (Remicade)FDA Link
11/2012
1Cyclosporine (Ciclosporin)FDA LinkGeneric
10/2012
1InterferonsIBA
02/2012
1AlbuminsIBA
02/2012
1Hepatitis B Surface Antigens (HBsAg)FDA Link
10/2011
1Hepatitis B e AntigensIBA
10/2011
1Alanine Transaminase (SGPT)IBA
10/2011
1DNA (Deoxyribonucleic Acid)IBA
10/2011
1Sodium-Glucose Transporter 2 InhibitorsIBA
09/2011
1Glucose (Dextrose)FDA LinkGeneric
09/2011
11,5- anhydro- 1- (5- (4- ethoxybenzyl)- 2- methoxy- 4- methylphenyl)- 1- thioglucitolIBA
09/2011
1Sodium-Glucose Transport ProteinsIBA
09/2011
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
07/2009
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
07/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2008
1LuciferasesIBA
11/2007

Therapy/Procedure

10Therapeutics
02/2015 - 01/2000
2Aftercare (After-Treatment)
03/2005 - 08/2000
2Injections
05/2004 - 06/2001
2Liver Transplantation
04/2001 - 08/2000
1Light Coagulation
05/2017
1Lasers (Laser)
05/2017
1Vitrectomy
05/2017
1Tooth Movement Techniques
08/2014
1Enteral Nutrition (Feeding, Tube)
11/2012
1Chemoradiotherapy
01/2010
1Blood Transfusion (Blood Transfusions)
09/2009